| Name: | Bradley D. Anderson |
| Position Type: | Professorship |
| Appointment Start Date: | 03/01/00 |
| Appointment End Date: | |
| Area of Specialty: | Drug delivery systems research |
| Summary Vita: | Education 1971, University of Kansas (Lawrence, KS), B.A. Chemistry 1978, University of Kansas (Lawrence, KS) M.S./Ph.D. Pharmaceutical Chemistry Thesis Title: "Specific Interactions in Nonaqueous Systems" Previous Positions 1990-2000, Professor, Department of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, University of Utah (Salt Lake City, UT) 2000-Present, Adjunct Professor, Department of Pharmaceutics and Pharmaceutical Chemisty, College of Pharmacy, University of Utah (Salt Lake City, UT) 2000-2002, H.B. Kostenbauder Professor and Chair, Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky (Lexington, KY) 2003-Present, H.B. Kostenbauder Professor, Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky (Lexington, KY) |
| Highest Degree: | Ph.D. |
| Professional Affiliations: | Invited Presentations/Contributed papers B.D. Anderson, "Molecular Dynamics Simulation of Reactant Mobility in an Amorphous Peptide Formulation", Pfizer, Inc., Groton, CT, March 2004. B.D. Anderson, "Anti-topoisomerase I Aerosols for Lung Cancer Therapy", Kentucky Lung Cancer Research Program Annual Scientist's Seminar, Lexington, KY, May 2004. B.D. Anderson, "Preformulation of Surface-Active Compounds", Roundtable Presentation, 2004 AAPS Pharmaceutics and Drug Delivery Conference, Philadelphia, PA, June 2004. B.D. Anderson, "Physicochemical and Biopharmaceutical Considerations in the Development of Poorly Water Soluble Compounds", Symposium Presentation, 2004 Professional Services Phi Lambda Upsilon Rho Chi American Chemical Society American Association for the Advancement of Science American Association of Pharmaceutical Scientists Biophysical Society |
| Primary Research Focus: | Pharmaceutics, Drug Delivery & Analysis |
| Key Contributions: | Permeabilities in Lipid Bilayer membranes, Enzyme-based Strategies for CNS Delivery of AIDS Drugs, Drug Decomposition in the Amorphous Solid-State and Development of Dosage Forms and Delivery Systems for Agents useful in the Treatment of AIDS and Cancer, Liposomal Delivery of Antitumor Agents |
| Publications: | T.-X. Xiang and B.D. Anderson, "A molecular dynamics simulation of reactant mobility in an amorphous formulation of a peptide in poly(vinylpyrrolidone)", J. Pharm. Sci., 93, 855-876 (2004). R.T. DeGraw and B.D. Anderson, "Determination of carrier mediated transport of 2',3'-dideoxypurine nucleosides in the rat ileum using an in situ bi-directional perfusion technique", Pharm. Res., 21, 300-308 (2004). Y. Cao, M. Marra and B.D. Anderson, "Predictive Relationships for the effects of triglyceride ester concentration and water uptake on solubility and partitioning of small molecules into lipid vehicles", J. Pharm. Sci., 93, 2768-79 (2004). L.M. Kinman, J.M. Worlein, L.K. Larsen, H. Bielefeldt-Ohmann, A.M. Schmidt, D.M. Anderson, S.-L. Hu, W.R. Morton, B.D. Anderson, and R.J.Y. Ho, "HIV in central nervous system and behavioral development - an HIV-2287 macaque model of AIDS", AIDS, 18, 1363-70 (2004). D. Luo, S.W. Smith, and B.D. Anderson, Kinetics and mechanism of the reaction of cysteine and hydrogen peroxide in aqueous solution, J. Pharm. Sci., 94, 304-316 (2005). Burke, T.G., T.-X. Xiang, B.D. Anderson, and L.J. Latus. "Recent Advances in Camptothecin Drug Design and Delivery Strategies" in Camptothecins in Cancer Therapy, in press. J.E. Edwards, J. Alcorn, J. Savolainen, B.D. Anderson, and P.J. McNamara, Role of p-glycoprotein in distribution of nelfinavir across the blood-mammary tissue barrier and blood-brain barrier, Antimicrob. Agents Chemother., 49, 1626-28 (2005). T.-X. Xiang and B.D. Anderson, Distribution and effect of water content on molecular mobility in poly(vinylpyrrolidone) glasses: A molecular dynamics simulation, Pharm.Res., in press. T.-X. Xiang and B.D. Anderson, Conformational structure, dynamics and salvation energies of small alanine peptides in water and carbon tetrachloride, J. Pharm. Sci., in press. |