||Bradley D. Anderson
|Appointment Start Date:
|Appointment End Date:
|Area of Specialty:
||Drug delivery systems research
1971, University of Kansas (Lawrence, KS), B.A. Chemistry
1978, University of Kansas (Lawrence, KS) M.S./Ph.D. Pharmaceutical Chemistry
Thesis Title: "Specific Interactions in Nonaqueous Systems"
1990-2000, Professor, Department of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, University of Utah (Salt Lake City, UT)
2000-Present, Adjunct Professor, Department of Pharmaceutics and Pharmaceutical Chemisty, College of Pharmacy, University of Utah (Salt Lake City, UT)
2000-2002, H.B. Kostenbauder Professor and Chair, Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky (Lexington, KY)
2003-Present, H.B. Kostenbauder Professor, Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky (Lexington, KY)
||Invited Presentations/Contributed papers
B.D. Anderson, "Molecular Dynamics Simulation of Reactant Mobility in an Amorphous Peptide Formulation", Pfizer, Inc., Groton, CT, March 2004.
B.D. Anderson, "Anti-topoisomerase I Aerosols for Lung Cancer Therapy", Kentucky Lung Cancer Research Program Annual Scientist's Seminar, Lexington, KY, May 2004.
B.D. Anderson, "Preformulation of Surface-Active Compounds", Roundtable Presentation, 2004 AAPS Pharmaceutics and Drug Delivery Conference, Philadelphia, PA, June 2004.
B.D. Anderson, "Physicochemical and Biopharmaceutical Considerations in the Development of Poorly Water Soluble Compounds", Symposium Presentation, 2004
Phi Lambda Upsilon
American Chemical Society
American Association for the Advancement of Science
American Association of Pharmaceutical Scientists
|Primary Research Focus:
||Pharmaceutics, Drug Delivery & Analysis
||Permeabilities in Lipid Bilayer membranes, Enzyme-based Strategies for CNS Delivery of AIDS Drugs, Drug Decomposition in the Amorphous Solid-State and Development of Dosage Forms and Delivery Systems for Agents useful in the Treatment of AIDS and Cancer, Liposomal Delivery of Antitumor Agents
||T.-X. Xiang and B.D. Anderson, "A molecular dynamics simulation of reactant mobility in an amorphous formulation of a peptide in poly(vinylpyrrolidone)", J. Pharm. Sci., 93, 855-876 (2004).
R.T. DeGraw and B.D. Anderson, "Determination of carrier mediated transport of 2',3'-dideoxypurine nucleosides in the rat ileum using an in situ bi-directional perfusion technique", Pharm. Res., 21, 300-308 (2004).
Y. Cao, M. Marra and B.D. Anderson, "Predictive Relationships for the effects of triglyceride ester concentration and water uptake on solubility and partitioning of small molecules into lipid vehicles", J. Pharm. Sci., 93, 2768-79 (2004).
L.M. Kinman, J.M. Worlein, L.K. Larsen, H. Bielefeldt-Ohmann, A.M. Schmidt, D.M. Anderson, S.-L. Hu, W.R. Morton, B.D. Anderson, and R.J.Y. Ho, "HIV in central nervous system and behavioral development - an HIV-2287 macaque model of AIDS", AIDS, 18, 1363-70 (2004).
D. Luo, S.W. Smith, and B.D. Anderson, Kinetics and mechanism of the reaction of cysteine and hydrogen peroxide in aqueous solution, J. Pharm. Sci., 94, 304-316 (2005).
Burke, T.G., T.-X. Xiang, B.D. Anderson, and L.J. Latus. "Recent Advances in
Camptothecin Drug Design and Delivery Strategies" in Camptothecins in Cancer Therapy, in press.
J.E. Edwards, J. Alcorn, J. Savolainen, B.D. Anderson, and P.J. McNamara, Role of p-glycoprotein in distribution of nelfinavir across the blood-mammary tissue barrier and blood-brain barrier, Antimicrob. Agents Chemother., 49, 1626-28 (2005).
T.-X. Xiang and B.D. Anderson, Distribution and effect of water content on molecular
mobility in poly(vinylpyrrolidone) glasses: A molecular dynamics simulation,
Pharm.Res., in press.
T.-X. Xiang and B.D. Anderson, Conformational structure, dynamics and salvation
energies of small alanine peptides in water and carbon tetrachloride, J. Pharm. Sci., in