Mass Spectrometry Facility
images of Mass Spectrometry

Mass Spectrometry Examples

MALDI

The choice of ionization method depends on the properties of the sample.

The choice of ionization method depends on the properties of the sample.

Small Molecules

Small molecules may be suitable for MALDI if they are readily ionizable. In positive ion mode, singly-charged ions produced by addition of H+ or Na+ are most common.

Maldi Small


Peptides

PMF


Proteins

Small proteins produce singly- and doubly-charged ions in MALDI-TOFMS.

Ubiquitin


Polymers

Peg Maldi


Organonometallics/Polyconjugated Aromatics

MALDI also works well for highly conjugated aromatic systems and some organometallic compounds. Ions may be produced by proton attachment or photoionization.

Maldi TOFMS Spectrum