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Auditing Subtype Inconsistencies among Gene Ontology Concepts

Rashmie Abeysinghe, CS Grad Student

Abstract: Gene Ontology (GO) provides a controlled vocabulary for describing genes and related gene products. Due to the sheer size and complexity of GO, manual review to discover terminology defects is infeasible. We introduce a lexical-based inference approach to detect subtype (or is-a) inconsistencies among GO terms (i.e., biological concepts).