Equipment

LTQ Velos Orbitrap with ETD

LTQ Velos Orbitrap with ETD

Ideal for identifying low abundance proteins and characterizing protein post-translational modifications. 

  • Superior Sensitivity at the sub-femtomole (< 10-15 moles) level
  • ETD (Electron transfer dissociation) — especially valuable for characterizing protein post-translational modifications
  • Front End: a dedicated Eksigent NanoLC-Ultra and NanoFlex ChipLC system
  • Non-splitting flow control
  • Outstanding reproducibility
  • Outstanding mass accuracy (routinely 1-2 ppm) and resolution (up to 100,000)
  • Microfluidic chips as columns
orbitrap machine
orbitrap machine wide view

TSQ Vantage Triple Quadrupole Mass Spec

TSQ Vantage Triple Quadrupole Mass Spectrometer

Workhorse of quantifying proteins, peptides and metabolites. i.e. biomarker validation and pharmacokinetics.

  • Linear dynamic range of four orders of magnitude for quantitation (0.01fmol-100fmol)
  • Multiple scanning modes: High-sensitivity full-scan, Selected Ion Monitoring (SIM), Selected Reaction Monitoring (SRM) and others
  • Quantitation-Enhanced Data-Dependent MS/MS (QED-MS/MS) for simultaneous compound confirmation and quantitation
  • Versatile HPLC front end:
    • Conventional flow with Shimadzu HPLC and electrospray (HESI-II) source
    • Capillary and Nano-flow with Eksigent HPLC and nanospray source
triple quad mass spec