Awarded Pilots

  • Konstantin Korotkov (College of Medicine) Inhibitors of Papain-like Protease from SARS-CoV-2
  • Charles Lutz (College of Medicine) Hypoxia-Induced Dysfunction of Virus-and Fibrosis-Fighting Human NK Cells-A Proposed Cure
  • Peter Nagy (College of Agriculture, Food and Environment) Identification of Cellular Targets of Human SARS-COV2 in Yeast
  • Jeremy Wood (College of Medicine) Dissecting the Underlying Mechanisms of Hemostatic Dysregulation in COVID-19 Patients
  • Beth Garvy (College of Medicine) Longitudinal Study of Immune Responses in COVID-19 Patients
  • Joel Hamm and James Keck (College of Medicine) STINCKY: Smell Testing for Infection with Novel Coronavirus in Kentucky
  • Becky Dutch (Molecular & Cellular Biochemistry) SARS-CoV-2 SPIKE PROTEIN STABILITY AND FUSION ACTIVITY: ROLES OF PROTEOLYTIC PROCESSING AND KEY RESIDUES:
  • Jill Turner (College of Pharmacy) CNS Involvement in the Progression of COVID-19: Preclinical Intervention with NMDA Receptor Antagonists
  • Lisa Cassis (Vice President for Research) Sex Differences in COVID-19
  • Oleg Tsodikov and Sylvie Garneau-Tsodikova (College of Pharmacy) Development of Ebselen/Ebsulfur Inhibitors of SARS-CoV-2 Main Protease Mpro for COVID-19 therapy

See brief project descriptions on CCTS site

Active Clinical Trials

  • Povidone-Iodine Intranasal for Prophylaxis in Front-Line Physicians and Inpatients during the SARS-CoV2 Pandemic (PIPPI)
    • Alexandra Kejner, Zach Porterfield, Rony Aouad, Adam Bastin, Melissa Batin, Matt Bush, Brett Comer, Laura Ebbit, Derek Forster, Thomas Gal, Nikita Gupta, Raleigh Jones, Joseph Valentino
  • Adaptive, Multi-Arm Phase II trial of Novel Agents for Treatment of High-Risk COVID-19 Positive Patients
    • Susanne Arnold, Zach Porterfield, Therese Bocklage, Miguel Villalona Calero, Rebecca Dutch, Jared Hammill, Elijah Kakani, Jill Kolesar, Zin Myint, Frank Romanelli, Alice Thornton, Heidi Weiss, Donglin Yang, Robert DiPaola, Kip Guy, Phil Kern