Awarded Pilots

  • Bradley Berron (College of Engineering) Hand Sanitizer Production: Bottleneck Analysis and Remediation
  • Louis Hersh and David Rodgers (College of Medicine) Production of Single Chain Antibodies (Nanobodies) to SARS-CoV-2 Spike Glycoprotein and its Receptor Binding Domain
  • Steven Van Lanen (College of Pharmacy) RNA-Dependent RNA Polymerase as an Antiviral Target
  • Daniel Pack (College of Engineering) Proton-Sponge Polymers for Inhibition of SARS-CoV-2 Infection
  • Jerold Woodward and Siva Gandhapudi (College of Medicine) Identification and Characterization of Virus Specific T Cells in Humans Exposed to SARS-COV-2

Advances in Detection

Woodward et al.

  • Robust, sensitive, and specific assay for SARS CoV2 antibodies in place
  • Established T cell assays to measure SARS CoV2 specific T cell responses from COVID convalescent patients

Scott Berry, et al.

  • Dramatically simplified ELISA strategy for improved ease of antibody testing
  • Working with Keck et al. on viral screening in municipal wastewater down to 10 copies / sample

Van Lanen, et al.

  • Built several protein constructs towards novel viral detection based on RNA polymerase activity

Clinical Tools

Pack et al.

  • Plasmids ready for production of lentiviruses pseudotypedwith SARS-CoV-2 spike protein
  • Screening of engineered proton sponges for inhibition of infection in coming weeks

Ohara et al.

  • IACUC cleared for remote tracking of breathing and other data in animal models of COVID infection

Agricultural Impacts

Stowe et al.

  • Detailed analysis of the pandemic impact on KY Equine markets and associated businesses
  • Four targeted surveys prepared for release pending IRB exemption

Zheng et al.

  • Analysis of market data to track trends in food and beverage consumption during COVID
  • Submitted paper on changes in food and beverage brand name association during COVID