2018 KNI Clinical-Translational Research Symposium | University of Kentucky Research

2018 KNI Clinical-Translational Research Symposium Abstracts

Cognitive Behavioral

The Triangle of Death of Neurons in Chemotherapy Induced Cognitive Impairment ("Chemobrain")

Potentially Inappropriate Medication Use and Incident Dementia in Privately-Insured Older Adults

White Matter Hyperintensity Regression is Associated with Better Executive Function

Effect of Long-term Dietary Vitamin D3 Supplementation on Cognition in Aging Male and Female F344 Rats

Origami Paper Folding Intervention Changes Alpha Oscillations Associated with Better Cognitive Ability in Normal Older Adults

Sex Differences in Brain Activity and Memory Performance Correlates in Healthy Older Adults

Cognitive Insight in the Stroke Population

Epilepsy Brain Metabolism

Seizure Prediction with Autonomic Measurements versus Intracranial EEG in Patients with Refractory Epilepsy

Epileptic Seizures in Aneurysmal Subarachnoid Hemorrhage: Predictive Factors and Utilization of Electroencephalography

Characterization of Sleep and Seizures in a Knockout Mouse Model of Lafora Disease

Extrinsic Regulation of Synaptic Connectivity and Neural Circuit Hyper-excitability by Cell Polarity Proteins

Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Anti-body Enzyme Fusion

Movement Neurodegenerative

Apomorphine-induced BOLD activations correlate with motor deficits and basal ganglia dysfunction in hemiparkinsonian rhesus macaques

Benefit of Inpatient Rehabilitation in Patients with Paramyotonia Congenita: A Case Report

Peripheral Nerve Grafts Implanted Into the Substantia Nigra in Patients with PD During DBS Surgery: 2-year Follow-up Study of Gait Parameters

Taste Function In early Stage Treated and Untreated Parkinson's Disease

Diverse Biochemical and Immunoflourescent Characteristics of Proteopathic Alpha-Synuclein in PD and MSA

Sural Nerve Grafting as a Disease Modifying Therapy for Parkinson's Disease

Neuro-Avatar: A Reverse Translational model of an Ongoing Cell Therapy Clinical Trial for Parkinson's Disease

Five-year Review of DBS Plus: A Clinical Trial Platform for Combining Delivery of Investigational Therapeutics with Deep Brain Stimulation Surgery

Four-week Anti-gravity Treadmill Gait Training in Individuals with Multiple Sclerosis: A Case Series

Neurotrauma

Exploring Approaches to Promote Respiratory Motor Plasticity Through Varied and Fixed Interval Intermittent Hypoxia

A Systematic Review of Closed Head Injury Models of Mild Traumatic Brain Injury in Rodents

Enhancing Motor Recovery with Brain Stimulation in Spinal Cord Injury

Aged Astrocytes Maladaptively Contribute to the Neuroinflammatory Milieu Following TBI

From Paralysis to Regrowth- Inducing Breathing Motor Recovery After Cervical Spinal Cord Injury

Acute Mitochondrial Impairment Underlies Prolonged Cellular Dysfunction After Repeated Mild Traumatic Brain Injuries

The Influence of the Microbiome on Brain and Gut Pathology After Traumatic Brain Injury

A Pharmacologic Neuroprotective Approach to Experimental TBI: Targeting Mitochondria & Lipid Peroxidation-derived Aldehydes

Neuromodulation Paired With Locomotor Training Improves Muscle Strength After Motor Complete Spinal Cord Injury: A Case Report

Pioglitazone Maintains Mitochondrial Bioenergetics via Binding to MitoNEET Following Spinal Cord Injury

Nanoparticle Delivery of miR-146 Altered the Expression of Macrophage/Microglia Makes Genes in Traumatic Injured Rat Brain

Electrophysiological Signatures of Detecting Malingered Brain Injury

Neurophysiology

The Effects of a Bacterial Endotoxin LPS: Neuromuscular Junction and Cardiac Function in Drosophilia Melanogaster and Phaenicia Sericata Larvae

Fibroblast Growth Factor 19 Alters Excitability in the Dorsal Motor Nucleus of the Vagus

Effects of TEA and 4-AP on Firing Frequency of Proprioceptive Neurons in Crustaceans

The Effects of a Ketogenic Diet on Behavior and Synaptic Transmission in a Drosophilia Model

The Influence of Endotoxic (LPS) on Primary Sensory Neurons in Crustaceans: Impact on Human Proprioception

Neurorehabilitation

Dose-response Relationship of Transcutaneous Spinal Direct Current Stimulation in Healthy Humans: A Proof of Concept Study

Nonpharmacological Regulation of the Ultradian Sleep-Wake Cycle in Mice

Effects of Fibularis Longus Dry Needling on Balance and Spinal Reflex Excitability in Healthy Adults

Neurovascular Stroke

Evaluation of Geographic Factors for Rural Patients Needing Access to Mechanical Thrombectomy At a Comprehensive Stroke Center

Dyshomeostasis of Pancreatic Amylin Provokes Hypoxia and Accelerates Aging

A Wearable Optical Sensor for Continuous Monitoring of Cerebral Blood Flow in Mice

Antithrombotic Bridging in Patients with Acute Ischemic Stroke and Atrial Fibrilation

Peri-Infarct Acid/Base and Electrolyte Alterations in Acute Large Vessel Occlusion Stroke

The Blood and Clot Thrombectomy Registry and Collaboration (BACTRAC) Protocol: Evaluation of Optimal RNA Extraction and Proteomic Analyses in Stroke

The Small Peptide ATN-161 as a Novel Potential Therapeutic for Vascular Disease

A Pilot Study Identifying Brain-targeting Adaptive Immunity in Pediatric ECMO Patients with Acquired Brain Injury

Development of a Semiautomated Volumetric Quantification Method for Cerebral Microbleed Using T2* Weighted Imaging

Implementation of an Early Mobilization Protocol in Acute Ischemic Stroke Patients Following Thrombolysis

Early Mobilization Following Recombinant Tissue Plasminogen Activator Administration and/or Mechanical Thrombectomy Reduces Length of Stay

Contemporary Seasonal Variations in Transient Ischemic Attack Hospitalizations in the United States: An Update on the Existing Literature

Disease Biomarkers Abstracts

CSF Amylin – Effect Modifier of the Aβ-AD Relationship

Analyses of Peripheral Blood Micro RNA Expression in Female Crack-Cocaine Dependents

Noninvasive Noncontact Speckle Contrast Diffuse Correlation Tomography of Cerebral Blood Flow in Rats

APOE Genotype Effect on Respiratory Quotient - A Potential Biomarker for Alzheimer's Disease Risk

Neuro Oncology

Patterns of Care, Operative Morbidity, and Survival of Cranial Chordomas: 10-year Analysis of the NCDB, SEER, and NSQIP Database

Brain Radiation Necrosis in a State-based Registry

Gliomatosis Cerebri: Disparities Beyond Molecular Similarities

Addiction

Crowdsourcing Health Behavior: Adverse Childhood Experiences, Tobacco Use, and Obesity

Outcomes/Health Services

Longer Average Length of Stay Predicts Increased Risk of Readmission, Complications, and Mortality at the Hospital Level in Psychiatric Patients

Sleep Disorders

A Non-invasive Alternative to Selective Sleep Restriction in Rodents Using Somatosensory Stimulation

Child Neurology

Inflammation and Oxidative Stress in Animal Models of Hydrocephalus

Neurotherapeutics

The Neurocognitive Effects of Exogenous βeta-hydroxybutyrate Administration in Non-clinical and a Clinical MTBI Case Series

Differential Effects of Non-invasive Brain Stimulation in Chronic Neuropathic Pain: Preliminary Findings of an Ongoing Double-blind Randomized Control

Other Neurodegenerative Diseases

Quantification of Siaiorrhea Reduction After Unilateral Parotid Electron Beam Radiotherapy in Debilitating Neurological Disorders

Changes in Microglia Across the Lifespan

Subset of Gene Expression Profiles in Human Post-mortem Brain Aging and AD are Robust, Concordant, and Show Exaggerated Changes in Female AD Subjects

Flow Cytometry Distinguishes Synaptosome Populations Containing a Progression of AD Pathologic Markers in Human Autopsy Brain and Tg Animal Model

2018 KNI Clinical-Translational Research Symposium Abstracts

Cognitive Behavioral

Epilepsy Brain Metabolism

Movement Neurodegenerative

Neurotrauma

Neurophysiology

Neurorehabilitation

Neurovascular Stroke

Disease Biomarkers Abstracts

Neuro Oncology

Addiction

Outcomes/Health Services

Sleep Disorders

Child Neurology

Neurotherapeutics

Other Neurodegenerative Diseases

Other Topics

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