Transforming Tomorrow By Finding Preventions and Treatments for Neurological Conditions

2016 KNI Clinical-Translation Research Symposium Abstracts

Traumatic Brain Injury Poster

Insulin-like Growth Factor-1 Overexpression Mediates Regional Alterations to the mTOR Signaling Pathway in the Hippocampus Following TBI

mTOR Inhibition After Controlled Cortical Impact Alters Hilar Interneuron Excitability

Synaptic Mitochondria Sustain More Damage than Non-Synaptic Mitochondria Following Traumatic Brain Injury and are Protected by Cyclosporine A 

Brain Injury Signaling Events After Expression of Mitochondria Associated microRNA

Phenelzine Administration following Traumatic Brain Injury Improves Mitochondrial FUnction and Reduces Lipid Peroxidation and Cytoskeletal Degradation

Effects of Controlled Cortical Impact Brain Injury on Cell Loss and Neurogenesis in the Mouse Dentate Gyrus

Activation of PERK in Controlled Cortical Impact Model of Traumatic Brain Injury

IL-1β Levels After TBI can be Inhibited with the Therapeutic MW151 without Affecting Microglial Physiological Responses

 
Memory/Aging Poster

Correlating Common TDP-43 and Tau Pathologic Patterns in the Aged Human Hippocampus

Manganese-Enhanced Magnetic Resonance Imaging (MEMRI)-Based Identification of Neuronal Dysfunction Before the Appearance Tau Pathology in rTg4510 Mice

Aβ Imaging Ligand Pittsburgh Compound B Binding in AD Frontal Cortical Synaptosomes is in Glutamatergic Synapses

Declines in Default-mode Network Structure and Function Mediate the Negative Effects of Alzheimer's Pathology on Executive Function in Older Adults 

Clinical Impact of MRI-Evident, Deep vs Periventricular T2 Abnormalities on Cognitive Impairment in Cerebrovascular Disease and Other Leukopathologies

A Multiple Ascending Dose Study of HDAC Inhibition for Modulation of Apoj/Clusterin Risk in Alzheimer's Disease

Acute Insulin Treatment of Hippocampal Neurons Highlights New Mechanisms of Action

Indentification of Novel Tau Interactions with Endoplasmic Reticulum Proteins in Alzheimer's Disease Brains

Aged Animals Appear Cognitively and Behaviorally Hyporesponsive to Chronic Restraint (Psychosocial Stress) Compared to Young Animals

Selective Modulation of Neuroinflammation by Targeting p38α MAPK with a Novel, Isoform-specific Inhibitor, MW150, in an Alzheimer's Disease Mouse Mode

The Role of Autophagy and the UPR in the Development of Alzheimer Disease in a Mouse Model of Down Syndrome Neuropathology

The Anti-NPI: A Novel Tool for Assessment of Neuropsychiatric Symptoms in Clinical Trials for Prodromal Alzheimer's Disease

 
Inflammatory Mechanism Poster

Intraneuronal Amylin Disposition, Peroxidative Membrane Injury and Increased IL-1β Synthesis in Brains of AD Patients with T2D and Diabetic HIP Rats

Microglia Heterogeneity in the Hippocampus of Alzheimer's Disease, Dementia with Lewy bodies, and Hippocampal Sclerosis of Aging

Addressing Innovation in CNS Drug Discovery: Functional or Single Molecular Target Approaches to Novel Compounds that Attenuate Synaptic Dysfunction

TREM-2 Induced Microglial Activation Promotes the Clearance of Amyloid-beta in an AD Mouse Model

Cognition and Affect in Possible Serial Autoimmune Episodes of Anti-NMDA-Receptor Encephalitis

Targeting Neuroinflammation in Vascular Cognitive Impairment with a Novel, CNS-Penetrant, Small Molecule Experimental Therapeutic

Therapeutic Approaches to Target Inflammation Following TBI Through Inhibition of the p38α MAPK
Recovery/Rehab Poster

Early Tracheostomy and Percutaneous Endoscopic Gastrostomy in Hemorrhagic Stroke Patients: Associated Factors and Effects on Hospitalization

Nerve Stimulation Paired with Task-Oriented Training Improves Chronic, Severe Hemiparesis After Stroke: A Randomized Trial

Closed Loop Afferent Electrical Stimulation for Recovery of Hand Function in Individuals with Motor Incomplete Spinal Injury: Early Clinical Results

Kentucky Care Coordination for Community Transitions (KC3T)

An Electromyography Study of Muscular Endurance during the Posterior Shoulder Endurance Test

Physician and Physical Therapist Communication is Associated with Earlier Mobility and Decreased Length of Stay in the Neuroscience Population

Optimizing Transcranial Direct Current Stimulation for Motor Recovery from Sever Post-stroke Hemiparesis

 

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