Human Research-IRB

Human Research/Institutional Review Board (IRB)

Road to Reaccreditation

UK's Human Research Protection Program (HRPP) brings together all constituents and stakeholders to protect the rights and welfare of research participants and build public trust in research. We demonstrate this commitment through accreditation by the Association for the Accreditation of Human Research Protection Programs (AAHRPP).

ORI has begun the arduous reaccreditation process which involves program review and a two-step application, culminating with a site visit assessment. At the site visit, AAHRPP will randomly select and interview researchers, staff, IRB members, and others involved in human subject research. Stay tuned for updates, training opportunities, and resources provided on our AAHRPP Re-Accreditation Website.




Find tools, checklists, E-IRB video tutorials and FAQs to help navigate the IRB review process.

IRB Membership

IRB Members

Find IRB reviewer checklists, guidance, IRB Rosters, IRB meeting dates, etc. 

Research Participants


What to consider before you agree to participate in a research study and other resources.

Latest ORI Educational Tools

Key Information Samples

New Video: "Don't Destroy Data"

Balancing confidentiality with data reproducibility requires researchers and IRB members to protect both research data and the participants from which it came. 

This brief animated video introduces how secure data retention can contribute to the reproduction and validation of research findings.   [HTML Video, 3:11]


UK Fact Sheet – Final NIH Policy for Data Management and Sharing 

The final NIH DMS Policy requires submission of Data Management and Sharing Plans and compliance with NIH Institute, Center, or Office-approved Plans. It also emphasizes the importance of good data management practices and establishes the expectation for maximizing the appropriate sharing of scientific data generated from NIH-funded or conducted research, with justified limitations or exceptions. Non-compliance may affect future NIH funding decisions. [PDF]

RCR In-Person Training/Discussion Sessions

As of January 1, 2024, new Human Research protocols cannot be submitted to the Institutional Review Board (IRB) for review and new Animal Research (IACUC) protocol submissions will be held from approval until the RCR training requirement is met and/or untrained University of Kentucky research personnel are removed. This includes both the online course completion as well as the in-person training session completion.

To register for a one (1) hour session, please visit the RCR In-Person Training/Discussion page. [HTML] Sessions are posted as they become available. Please keep in mind the sessions have limited seating availability.

If you would like to be an RCR Trainer for your area and/or other areas, visit our website for more information. [HTML]

iThenticate at UK


The Vice President for Research (VPR) has purchased an iThenticate subscription for researchers including graduate students.  iThenticate (plagiarism-checking software) is now available for RCR-compliant researchers including graduate students.   

Request Access [HTML]


About ORI

 ORI supports the institution in promoting ethical conduct of human research and educating University of Kentucky (UK) faculty, staff, and students regarding human research compliance and research ethics.  

ORI provides research support services including IRB review, policy development, web-based IRB submission (E-IRB), HIPAA/FERPA research reviews, protocol review management, ethical and regulatory education, quality improvement review, reliance agreement management, and research misconduct prevention and allegation management. ORI provides support for six federally mandated review committees: four Medical and one Nonmedical Institutional Review Boards (IRB), and the Radioactive Drug Research Committee (RDRC).  

The UK Human Research Program is fully accredited by the Association for the Accreditation of Human Research Protection Program (AAHRPP). Read about the 2020 AAHRPP Re-accreditation here. Follow the road to the 2025 Re-accreditation here.

UK Human Research Protection Program (HRPP) Comprehensive Plan (PDF, 22 pgs)


Award of Excellence for Best Practice in Human Research Protection

In December 2018, the University of Kentucky Office of Research Integrity (ORI) won an Award of Excellence for Best Practice in Human Research Protection for the “Informed Consent Workshop: From Perception to Process.” The four-hour, hands-on workshop assists researchers in adopting new informed consent rules. Read more…