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In the past 12 years, the gala celebrating a proud Kentucky tradition has raised and donated approximately $16.7 million to combat a disease that disproportionally affects Kentucky.

A new University of Kentucky College of Medicine study provides insight into how a protein called angiotensinogen (AGT) contributes to blood pressure regulation and atherosclerosis.

By means of open access, Progress in Scale Modeling stands out as a barrier-free venue to disseminate peer-reviewed research for the benefit of society, scholarship and humanity.

“We operate as a single team, combining our expertise in order to tackle the complex multi-physics problems that arise in astrophysics — problems that are beyond the capacity of a single investigator.”

The challenge, Moseley says, is in analyzing this complex data to derive new biological knowledge and in making this data and knowledge available in a highly reusable format in public scientific repositories.

Through the group's work, they found that the therapeutic targeting of TREM2 using a TREM2-activating antibody leads to the activation of microglia, recruitment of microglia to amyloid plaques, reduced amyloid deposition, and ultimately improved cognition.

“We used to think that aging-related memory and thinking decline meant one thing: a disease called Alzheimer’s disease. Now we know that the disease we were calling Alzheimer’s disease is actually many different conditions, often in combination."

"When I came to the U.S. and was confronted with the health care system here, I wasn’t comfortable practicing medicine without doing something to serve people who don’t have proper access to care because they’re uninsured or far from services."

The team suggests a number of changes to help rebuild trust and reduce stigma for opioid use disorder in rural communities; they also suggest that wholesalers change algorithms to track buprenorphine separately from other opioids.

Coal-to-carbon fiber research shows great promise to positively impact the nation’s sluggish coal industry. In 2019, U.S. coal production, consumption and employment reached their lowest levels in 40 years.