Clinical Trials
  • Article
  • Feb 1 2021

The Phase 3 randomized, double-blind, placebo-controlled clinical trial was designed to evaluate the safety and efficacy of a single vaccine dose of the Janssen investigational COVID-19 vaccine candidate versus placebo. Approximately 45,000 people participated worldwide. The combined UK, Baptist and Norton site was among the top enrolling sites in the world.

  • Article
  • Jan 12 2021

A new study by UK Markey Cancer Center researchers shows that DACH1 mutations are prevalent in Kentucky patients with endometrial cancer, suggesting that DACH1 may be a candidate biomarker for future trials with immunotherapy.

  • Podcast
  • Nov 20 2020

Dr. Peter Nelson, of the University of Kentucky’s Sanders-Brown Center on Aging, has spent the last 15 years in the Commonwealth helping to lead the fight against Alzheimer’s and dementia inducing brain disease.

  • Article
  • Nov 5 2020

Janssen’s AdVac® technology was used to develop Janssen’s Ebola vaccine regimen and is the basis for its HIV, RSV and Zika vaccine candidates.

  • Article
  • Oct 29 2020

Building on these findings, Plattner and Markey oncologists are now collaborating with the pharmaceutical company Novartis to develop a Phase I clinical trial to test the safety and effectiveness of using nilotinib in relapsed melanoma patients.

  • Article
  • Oct 22 2020

A team of Health Sciences investigators are collaborating with military researchers at the Naval Health Research Center and faculty at the University of Virginia to find rehabilitative solutions for populations most at risk for chronic and future ankle injuries.

  • Article
  • Sep 8 2020

The funding will further ongoing substance use disorder treatment research in collaboration with Sharon Walsh at the UK Center on Drug and Alcohol Research (CDAR) and Mei-Chuan Ko at the Wake Forest School of Medicine.

  • Video
  • Aug 11 2020

Artemisia annua or "Sweet Annie" has been used as a medicinal herb for centuries. With potential to treat a variety of cancers & even COVID-19, this plant is more relevant than ever & UK is showing how we can take it from Kentucky fields to the lab to our patients.

  • Article
  • Aug 3 2020

UK researchers hope to gain a better understanding of the effects of COVID-19 on sleep and alcohol use so that we will be better prepared to prevent and treat psychological effects of COVID-19 pandemic or similar outbreaks in the future.

  • Article
  • Jul 29 2020

For the past several decades, much of the work to find a treatment for AD has been focused on eliminating those dreaded Aβ plaques, by assuming that memory could be restored by removing the plaques.